| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2065393 | Toxicon | 2008 | 5 Pages |
Abstract
Bacillus anthracis secretes two binary toxins: lethal toxin (PA + LF) and edema toxin (PA + EF) that play a major role in the pathogenesis of anthrax. Their activities can synergize or interfere among each other, depending on the cell type. It is therefore fundamental to know their concentration ratio in vivo. Here, we report the first determination of the concentration ratio of anthrax toxin components LF/EF in the serum of rabbits infected with B. anthracis spores.
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Authors
Federica Dal Molin, Antonio Fasanella, Morena Simonato, Giuliano Garofolo, Cesare Montecucco, Fiorella Tonello,