| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2066304 | Toxicon | 2006 | 4 Pages |
Abstract
The amino acid sequence of actinoporin RTX-A (175 aa) from the sea anemone Radianthus macrodactylus was determined by sequencing of clones obtained via amplification of cDNA. It was established that RTX-A possessed high homology with HmgIII from Heteractis magnifica (87%) and StI, StII from Stichodactyla helianthus (84 and 87%, respectively). The analysis of structural and functional relationships within RTX-A was carried out. The some disagreement concerning to significant role of several amino acid residues for actinoporins exhibition of hemolytic activity was found.
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Authors
Anna Il'ina, Aleksey Lipkin, Ekaterina Barsova, Marina Issaeva, Elena Leychenko, Konstantin Guzev, Margarita Monastyrnaya, Sergey Lukyanov, Emma Kozlovskaya,