Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2066597 | Toxicon | 2008 | 7 Pages |
Abstract
The effects of 48Â h okadaic acid (OA) treatment and the ability to recover the induced toxicological injuries were examined in Enchytraeus crypticus of different ages (25 days and 3 months). The results demonstrated that the older worms are more sensitive to the toxin and show less capacity to recover. After 48Â h OA treatment, the structural organization of the chloragogenous tissue appeared modified and associated with an immune response involving a higher number of circulating coelomocytes immunoreactive to anti-IL-6 antibody. The toxin effects were more evident in 3-month-old animals compared to specimens aged 25 days. Regarding the morpho-functional recovery from the induced modifications, first signs of recuperation were observed in younger worms at 48Â h, and recovery was almost complete within 1 week. In older animals, the morphology of the chloragogenous tissue had not been restored, while a reduction in coelomocyte number was found after 1 week.
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Authors
A. Franchini, E. Ottaviani,