Article ID Journal Published Year Pages File Type
2070505 Progress in Biophysics and Molecular Biology 2007 11 Pages PDF
Abstract

An experimental study using a mason horn of 21.4 kHz indicated that the threshold shear stress for cell sonoporation was 12±4 Pa for ultrasound exposure time up to 7 min. Numerical calculations have shown that shear stress associated with microstreaming surrounding encapsulated bubbles may be large enough to generate sonoporation at 0.1 MPa of 1 or 2 MHz ultrasound.

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