Article ID Journal Published Year Pages File Type
2070611 Progress in Biophysics and Molecular Biology 2010 6 Pages PDF
Abstract
Complex signal-transduction cascades are known to be involved in regulating cardiomyocyte function, death and survival during acute cardiac ischemia-reperfusion process, but detailed survival signalling pathways are not clear. This review presents and discusses the recent findings bearing upon the evidence on the cardioprotective effect of sphingosine-1-phosphate (S1P) and bradykinin in acute cardiac ischemia-reperfusion and underlying signalling mechanisms, particularly, through activation of P21 activated kinase.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biophysics
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