| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2071041 | Advanced Drug Delivery Reviews | 2012 | 7 Pages |
Abstract
In this review, we discuss recent developments in the delivery of adeno-associated virus-based vectors (AAV), particularly with respect to the role of axonal transport in vector distribution in the brain. The use of MRI-guidance and new stereotactic aiming devices have now established a strong foundation for neurological gene therapy to become an accepted procedure in interventional neurology.
Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (366 K)Download as PowerPoint slide
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biotechnology
Authors
Ernesto A. Salegio, Lluis Samaranch, Adrian P. Kells, John Forsayeth, Krystof Bankiewicz,