Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2071169 | Advanced Drug Delivery Reviews | 2012 | 12 Pages |
Abstract
Non-invasive treatment of injuries and disorders affecting bone and connective tissue remains a significant challenge facing the medical community. A treatment route that has recently been proposed is nitric oxide (NO) therapy. Nitric oxide plays several important roles in physiology with many conditions lacking adequate levels of NO. As NO is a radical, localized delivery via NO donors is essential to promoting biological activity. Herein, we review current literature related to therapeutic NO delivery in the treatment of bone, skin and tendon repair.
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Biotechnology
Authors
Scott P. Nichols, Wesley L. Storm, Ahyeon Koh, Mark H. Schoenfisch,