Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2071339 | Advanced Drug Delivery Reviews | 2011 | 10 Pages |
Abstract
The combination of aptamers with novel nanomaterials, including nanomaterial-based aptamer bioconjugates has attracted considerable interest and has led to a wide variety of applications. In this review, we discuss how a variety of nanomaterials, including gold, silica and magnetic nanoparticles, as well as carbon nanotubes, hydrogels, liposomes and micelles, have been used to functionalize aptamers for a variety of applications. These aptamer functionalized materials have led to advances in amplified biosensing, cancer cell-specific recognition, high-efficiency separation, and targeted drug delivery.
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Authors
Liu Yang, Xiaobing Zhang, Mao Ye, Jianhui Jiang, Ronghua Yang, Ting Fu, Yan Chen, Kemin Wang, Chen Liu, Weihong Tan,