Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2072132 | Advanced Drug Delivery Reviews | 2013 | 22 Pages |
Abstract
Topical delivery to the various regions of the skin and underlying tissues, transdermal drug delivery and dermal exposure to environmental chemicals are important areas of research. Mathematical models of epidermal and dermal transport, involving penetration of a solute through various layers of the skin, metabolism in the skin and its subsequent distribution and clearance into systemic circulation from underlying tissues, play an essential role in this research area and are reviewed in this work.
Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (304 K)Download as PowerPoint slide
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biotechnology
Authors
Yuri G. Anissimov, Owen G. Jepps, Yuri Dancik, Michael S. Roberts,