Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2075844 | Biosystems | 2015 | 6 Pages |
Abstract
We introduce a novel web-based tool, miSEA, for evaluating the enrichment of relevant microRNA sets from microarray and miRNA-Seq experiments on paired samples, e.g. control vs. treatment. In addition to a group of previously annotated microRNA sets embedded in the system, this tool enables users to import new microRNA sets obtained from their own research. miSEA allows users to select from a large variety of microRNA grouping categories, such as family classification, disease association, common regulation, and genome coordinates, based on their requirements. miSEA therefore provides a knowledge-driven representation scheme for microRNA experiments. The usability of this platform was discerned with a cancer type-classification task performed on a set of real microRNA expression profiling experiments. The miSEA web server is available at http://www.baskent.edu.tr/â¼hogul/misea
Keywords
Related Topics
Physical Sciences and Engineering
Mathematics
Modelling and Simulation
Authors
M.Erdem ÃorapçıoÄlu, Hasan OÄul,