Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2076235 | Biosystems | 2010 | 8 Pages |
Abstract
We investigate the distribution of pointers for all currently sequenced micronuclear ciliate genes with the goal of identifying what distinguishes the real gene structure among all possible coding/noncoding divisions. We find a sharp criterion in the average a/t-content of the noncoding blocks: the real division has, in most cases, the maximum such content among all possible combinations. Even for pointers as short as two nucleotides, the real division is one of very few with an average a/t-content of its noncoding blocks over 80%. The separation is most clear when the loci of pointers of up to four nucleotides (even three in the case of unscrambled genes) are fixed (e.g., through a template-based recombination mechanism).
Keywords
Related Topics
Physical Sciences and Engineering
Mathematics
Modelling and Simulation
Authors
Sergey Verlan, Artiom Alhazov, Ion Petre,