Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2076977 | Biosystems | 2007 | 11 Pages |
Abstract
How a developing embryo becomes “informed” about its form?” This problem remains obscure and controversial. We argue that the “information about a form” is distributed throughout three main components: the dynamic laws, the parameters and the initial/boundary conditions. In the absence of a dynamic law two other components are “blind”, that is, do not contain any unambiguous information. We present a version of a dynamic law of morphogenesis, based upon the presumption of a feedback between passive and active mechanical stresses. We explore several models of shape formation based upon this law and show that, as depending upon the parameters values, they generate a large set of realistic shapes. Genetic and epigenetic basis of the models parameters is discussed.
Keywords
Related Topics
Physical Sciences and Engineering
Mathematics
Modelling and Simulation
Authors
Lev V. Beloussov, Vassily I. Grabovsky,