Article ID Journal Published Year Pages File Type
2077190 Biosystems 2007 7 Pages PDF
Abstract

It is explained how going from a one headed motor protein to a stepping two headed motor protein is equivalent to going from a stochastically flashing ratchet to a feedback control ratchet. Both these ratchets have been well studied in the literature and their speeds and efficiencies are briefly reviewed. Next it is shown how a feedback control ratchet mechanism model can account for very accurate recent data obtained on kinesin. Finally, the role of internal friction in the operation of stepping motor proteins is discussed.

Related Topics
Physical Sciences and Engineering Mathematics Modelling and Simulation
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