| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2077568 | Cell Stem Cell | 2012 | 8 Pages |
Abstract
Over the past 10 years, increasing evidence has accumulated that heterogeneity is a feature of hematopoietic stem cell (HSC) proliferation, self-renewal, and differentiation based on examination of these properties at a clonal level. The heterogeneous behavior of HSCs reflects the operation of a complex interplay of intrinsic and extrinsic variables. In this review, we discuss key findings from the last 5 years that reveal new insights into the mechanisms involved.
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Authors
Michael R. Copley, Philip A. Beer, Connie J. Eaves,