Article ID Journal Published Year Pages File Type
2077572 Cell Stem Cell 2012 11 Pages PDF
Abstract

Germline stem cells are key to genome transmission to future generations. Over recent years, there have been numerous insights into the regulatory mechanisms that govern both germ cell specification and the maintenance of the germline in adults. Complex regulatory interactions with both the niche and the environment modulate germline stem cell function. This perspective highlights some examples of this regulation to illustrate the diversity and complexity of the mechanisms involved.

Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biotechnology
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