Ethical Standards for Human-to-Animal Chimera Experiments in Stem Cell Research

The purpose of this report is to offer investigators and members of SCRO and animal research committees well-grounded ethical standards for evaluating research involving the transfer of multipotent and pluripotent human stem cells and their direct derivatives into animal systems. This report is deliberately written in general terms so that its recommendations can apply to diverse institutions and international settings. Thus, investigators and reviewers should aspire to these proposed ethical standards while exercising appropriate judgment in individual situations.