| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2078041 | Cell Stem Cell | 2011 | 4 Pages |
Abstract
Polycomb group (PcG) proteins regulate gene expression in embryonic and adult stem cells, but the mechanisms responsible for PcG gene targeting and regulation remain largely unknown. Recent evidence shows that EZH2, the enzymatic subunit of Polycomb Repressive Complex 2 (PRC2), is a nuclear phosphoprotein linking cell-cycle-intrinsic or extracellular signals to specific epigenetic signatures.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biotechnology
Authors
Giuseppina Caretti, Daniela Palacios, Vittorio Sartorelli, Pier Lorenzo Puri,