Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2078388 | Cell Stem Cell | 2007 | 11 Pages |
Abstract
For the past 30 years, the prevailing model of epidermal homeostasis has been that epidermal stem cells give rise to transit amplifying cells, which undergo a limited number of cell divisions before initiating terminal differentiation. Recent studies challenge the existence of a transit amplifying cell compartment and suggest a new paradigm for epidermal homeostasis.
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Authors
Philip H. Jones, Benjamin D. Simons, Fiona M. Watt,