Article ID Journal Published Year Pages File Type
2078964 Chinese Journal of Biotechnology 2007 6 Pages PDF
Abstract
The physiological roles of the glutathione (GSH)/glutathione peroxidase (GPx) system in protecting microbial cells against oxidative stress were reviewed. The GSH/GPx system is obligatory for maintaining the redox balance and defending the oxidative stress in Saccharomyces cerevisiae, a model eukaryotic organism. However, the system only conditionally exists in prokaryotes. That is, for those prokaryotic bacteria containing glutathione reductase and GPx, e.g. Haemophilus influenzae and Lactococcus lactis, by taking up GSH, they might develop a conditional GSH-dependent GPx reduction system, which conferred the cells a stronger resistance against oxidative challenge.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biotechnology
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