Article ID Journal Published Year Pages File Type
2079381 Computational and Structural Biotechnology Journal 2012 12 Pages PDF
Abstract

The combination of computational and directed evolution methods has proven a winning strategy for protein engineering. We refer to this approach as computer-aided protein directed evolution (CAPDE) and the review summarizes the recent developments in this rapidly growing field. We will restrict ourselves to overview the availability, usability and limitations of web servers, databases and other computational tools proposed in the last five years. The goal of this review is to provide concise information about currently available computational resources to assist the design of directed evolution based protein engineering experiment.

Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biotechnology
Authors
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