Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2079928 | Drug Discovery Today | 2014 | 13 Pages |
Abstract
- Angiotensin-converting enzyme inhibitors are an important class of drugs, which exhibits the potential for further development.
- A crucial point of ACE-I discovery is the comprehension of the biology of their molecular target.
- The insight of historical aspect of ACE-I design lays the foundation for appropriate SAR studies.
- Finding the mathematical relationship between potency or stability and structure facilitates the process of ACE-I development.
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Authors
Katarzyna Regulska, Beata Stanisz, MiÅosz Regulski, Marek Murias,