One hundred thousand mouse clicks down the road: selected online resources supporting drug discovery collected over a decade

•There are many in silico resources and databases that can assist drug discovery; yet it is almost impossible to track all these new services.•We provide a comprehensive list of drug design tools collected over the course of a decade.•Our directory contains over 1500 URLs.•We illustrate the value of our weblinks for certain selected areas.•We comment some ongoing and future efforts in the field.

Online resources enabling and supporting drug discovery have blossomed during the past ten years. However, drug hunters commonly find themselves overwhelmed by the proliferation of these computer-based resources. Ten years ago, we, the authors of this review, felt that a comprehensive list of in silico resources relating to drug discovery was needed. Especially because the internet provides a wealth of inspiring tools that, if fully exploited, could greatly assist the process. We present here a compilation of online tools and databases collected over the past decade. The tools were essentially found through literature and internet searches and, currently, our list contains over 1500 URLs. We also briefly highlight some recently reported services and comment about ongoing and future efforts in the field.

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