Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2080132 | Drug Discovery Today | 2012 | 8 Pages |
Complete with extraordinary structures and properties, carbon nanotubes (CNTs) have recently emerged as a potential new option for use in cancer treatment. During recent years, cancer cell lines have also been explored as prominent experimental models for evaluating pharmacokinetic parameters, cell viability, cytotoxicity and drug efficacy in tumor cells. Thus, cell lines have emerged as the best-fit model that has been thoroughly investigated and explored. This review focuses on potential applications and a compilation of various cancer cell lines used to evaluate CNT efficacy on one platform. This is likely to aid the researchers in exploring another dimension of CNTs in cancer treatment.
► CNTs: promising tool in cancer diagnosis and therapy. ► One platform comparison of CNTs efficacy in various cancer cell lines. ► Benchmark selection of cell lines for ex vivo studies in cancer research. ► Validating cell lines as a modality to evaluate system efficacy.