Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2080396 | Drug Discovery Today | 2011 | 10 Pages |
Abstract
Portfolio management in drug development has become a best practice in the pharmaceutical industry. By contrast, early on in the value chain – the discovery phase – portfolio management is still in its infancy. Nevertheless, owing to the attrition of R&D projects from phase to phase and the cost of capital involved, these early phases of drug discovery play a significant part for the overall cost of bringing new, innovative drugs to the market. This paper describes various approaches to manage a portfolio of projects in early-stage drug discovery and provides crucial factors that determine the success of such an approach.
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Authors
Ulrich A.K. Betz,