| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2081231 | Drug Discovery Today | 2006 | 8 Pages |
Abstract
Unlike traditional biological research that focuses on a small set of components, systems biology studies the complex interactions between a large number of genes, proteins and other elements of biological networks and systems. Host–pathogen systems biology examines the interactions between the components of two distinct organisms, either a microbial or viral pathogen and its animal host or two different microbial species in a community. With the availability of complete genomic sequences of various hosts and pathogens, together with breakthroughs in proteomics, metabolomics and other experimental areas, the investigation of host–pathogen systems on a multitude of levels of detail has come within reach.
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Authors
Christian V. Forst,