Article ID Journal Published Year Pages File Type
2081293 Drug Discovery Today 2014 8 Pages PDF
Abstract

•MNPs act as theranostic agents because of intrinsic magnetic properties.•MNPs act as a diagnostic tool by acting as contrast agents for MRI.•MNPs can deliver drugs or genes in a targeted manner by utilizing external magnetic field.•Magnetic hyperthermia uses MNPs to increase the temperature and kill cancer cells.•MNPs have reached clinical trials for cancer diagnosis and therapy.

Multifunctional nanoplatforms represent a cutting edge tool in biomedical applications as a result of their applicability in the concurrent monitoring of medical treatment. Magnetic nanoparticles (MNPs) have generated great interest in the field of cancer nanotheranostics owing to their intrinsic magnetic property that enables them to be used as contrast agents in magnetic resonance imaging and as a therapeutic system in conjunction with hyperthermia. In addition, the physical properties and biocompatibility of MNPs help them to act as efficient drug carriers for targeted therapeutic regimes. In this review, we have discussed the different theranostic applications of MNPs. Further, we have raised the current challenges associated with the clinical translation of MNPs along with future opportunities in this field.

Graphical abstractThe different applications of magnetic nanoparticles that make them suitable as theranostic agents.Figure optionsDownload full-size imageDownload high-quality image (190 K)Download as PowerPoint slide

Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biotechnology
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