| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2081787 | Drug Discovery Today: Disease Mechanisms | 2010 | 8 Pages |
Abstract
Obesity is characterized by ‘low grade’ and chronic inflammation, which leads to pathologies such as insulin resistance, type 2 diabetes or atherosclerosis. The role of the adipose tissue, and specifically adipocytes, in this process is discussed.Besides, the palmitoylethanolamide (PEA), an endocannabinoid-like molecule, was revealed to have an overall anti-inflammatory effect; moreover, it is secreted by adipose tissue. Thus, this review aims to understand the role of PEA in adipocytes in the case of obesity-related inflammatory states.
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Authors
Laurence Hoareau, Régis Roche,