| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2081793 | Drug Discovery Today: Disease Mechanisms | 2010 | 7 Pages |
Abstract
Heart failure (HF) in which the blood supply does not match the body's needs, affects 10% of the population over 65 years old. The protein kinase C (PKC) family of kinases has a key role in normal and disease states. Here we discuss the role of PKC in HF and focus on the use of specific PKC regulators to identify the mechanism leading to this pathology and potential leads for therapeutics.
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Authors
Nir Qvit, Daria Mochly-Rosen,