Article ID Journal Published Year Pages File Type
2081808 Drug Discovery Today: Disease Mechanisms 2010 6 Pages PDF
Abstract

There is a growing appreciation of the important role of small RNA (sRNA) molecules in post-transcriptional regulation of bacterial gene expression. sRNA transcripts are encoded within intergenic regions or in antisense orientation to mRNA transcripts, and sRNA regulation plays a central role in the response to stress stimuli encountered by pathogens during infection. We discuss the potential importance of sRNA in the pathogenesis of Mycobacterium tuberculosis.

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