Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2082046 | Drug Discovery Today: Disease Models | 2014 | 7 Pages |
Abstract
A paradigm shift in nucleic acid sequencing has spurred the development of molecular and computational techniques for the quantitative detection of epigenetic modifications genome-wide. Collectively, these methods provide researchers with an epigenomic 'tool kit' to engage in the molecular characterization of epigenetic states at a scale not imagined only a few years ago. This review provides a description of the current state of the massively parallel sequencing based epigenomic tool kit.
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Authors
Matthew Mingay, Martin Hirst,