Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2082125 | Drug Discovery Today: Disease Models | 2014 | 9 Pages |
Abstract
This review discusses the suitability and advantages of teleost fish for studying underlying mechanisms of normal and pathological development and mineralization of vertebrate skeleton, presents a selection of zebrafish mutants and transgenic lines modeling human skeletal diseases and highlights currently available fish systems for identifying and characterizing novel osteogenic and osteotoxic molecules.
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Authors
Vincent Laizé, Paulo J. Gavaia, M. Leonor Cancela,