| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2082178 | Drug Discovery Today: Disease Models | 2008 | 7 Pages |
Abstract
The ultimate goal in organ transplantation is to reach a state of tolerance to the graft so that immunosuppression is no longer needed. Rodent models have been poor predictors for translating new approaches to the clinic. Non-human primates (NHP) are considered an essential step between rodent and application in humans. This review describes the models available and when to use them.
Section editors:Margreet Jonker, Michel Vierboom and Bert 't Hart – Biomedical Primate Research Centre BPRC, Rijswijk, The Netherlands
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Authors
Krista G. Haanstra, Margreet Jonker,