| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2082190 | Drug Discovery Today: Disease Models | 2009 | 5 Pages |
Abstract
Epithelial to mesenchymal transition (EMT) is a highly conserved programme of events essential for normal development. As it underpins cell plasticity, migration and invasion in a number of settings it is an attractive concept to apply to the malignant phenotype. Much is known about the molecular events regulating EMT in a number of model organisms, including Drosophila, sea urchin, zebrafish, xenopus and the chick. It is increasingly apparent that EMT is a highly conserved process, and that discoveries made in these systems provide excellent insights into the understanding of the role of EMT in human malignancies.
Section editor:Robert M. Mader – Department of Medicine I, Medical University of Vienna, Vienna, Austria
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Authors
Nur Akmarina B.M. Said, Elizabeth D. Williams,