Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2082338 | Drug Discovery Today: Disease Models | 2006 | 6 Pages |
Abstract
Studies regarding the role of T cells in allergic asthma have been facilitated by the development of mouse models of this disease. Although these models do not accurately reflect human asthma they mimic cardinal asthma manifestations. T helper type 2 lymphocytes are considered as the main effector cells in the pathology, however, new T cells subtypes have been characterized during the past decade, which have greatly extended our vision on the immunoregulation of this disease.
Section editor:Nelly Frossard – Faculté de Pharmacie, Université Louis Pasteur, Illkirch, France
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Authors
Alexandre C. Motta, Antoon J.M. van Oosterhout,