Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2082561 | Drug Discovery Today: Technologies | 2012 | 9 Pages |
Abstract
Oral delivery of drugs with poor aqueous solubility and poor enzymatic and/or metabolic stability is very challenging. However, the advent of nanotechnology has revolutionized the field of oral drug delivery. The review provides an overview of various nano-architectures such as nanosuspensions, lipid and polymeric nanocarriers, inorganic nanostructures and describes advantages and challenges associated with their efficient delivery. Among various nano-architectures, only nanosuspensions and spontaneously emulsifying systems have succeeded in reaching pharmaceutical market.
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Authors
Preshita P. Desai, Abhijit A. Date, Vandana B. Patravale,