| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2082565 | Drug Discovery Today: Technologies | 2012 | 10 Pages |
Abstract
Today, prodrugs are an important option in any lead optimization program and are being considered as soon as critical hurdles in terms of solubility and permeability are identified. A successful prodrug effort starts with a careful evaluation of the issues and is guided by a detailed stepwise characterization of solubility, stability and permeability to arrive at an efficient optimization process.
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Authors
Hans Maag,