The use of micro-CT to study bone architecture dynamics noninvasively

High-resolution micro-CT has become a standard tool in the evaluation of bone architecture. It has recently progressed from an invasive tool for bone specimens into an in vivo tool for small animals. The combination of novel sophisticated evaluation methods, such as registration (matching) of sequential scans and computer simulation models will further evolve in vivo micro-CT into an optimal tool for small animal phenotyping and contemporary approaches for drug discovery relating to the skeleton.

Section editors:Bart Ellenbroek – Radboud University, Nijmegen, The NetherlandsTwan Ederveen – N.V. Organon, Oss, The Netherlands