| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2082749 | Drug Discovery Today: Technologies | 2011 | 7 Pages |
Abstract
The quantitative application of PET neuroreceptor imaging to study pathophysiology, diagnostics and drug development has continued to benefit from associated advances in biomathematical imaging methodology. We review some of these advances with particular focus on multi-modal image processing, tracer kinetic modeling, occupancy studies and discovery and development of novel radioligands.
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Authors
Roger N. Gunn, Qi Guo, Cristian A. Salinas, Andri C. Tziortzi, Graham E. Searle,