| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2082794 | Drug Discovery Today: Technologies | 2006 | 9 Pages |
Abstract
Most proteins show characteristic biological roles after modification with carbohydrates, and profiling of total carbohydrates (glycans) has been a big target for a full understanding of protein functions. Owing to extreme heterogeneity of the glycans, high sensitivity and high resolving power are required for their analysis. Combination of techniques using high-performance liquid chromatography, capillary electrophoresis and mass spectrometry allows comprehensive analysis of glycans derived from biological sources.
Section editors:Harald John – Bundeswehr, Institute of Pharmacology and Toxicology, Munich, GermanyRainer Bischoff – Centre of Pharmacy, University of Groningen, The Netherlands
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Authors
Miyako Nakano, Akihiro Kondo, Kazuaki Kakehi, Naoyuki Taniguchi,