Article ID Journal Published Year Pages File Type
2082916 Drug Discovery Today: Therapeutic Strategies 2010 6 Pages PDF
Abstract
Immunotherapy for prostate cancer became a therapeutic option for metastatic castration-resistant prostate cancer after a phase III trial of sipuleucel-T demonstrated an overall survival advantage relative to placebo. A similar phase II trial in the same population but with the vaccine PSA-TRICOM also demonstrated an overall survival advantage. As these and similar immunotherapeutic options for prostate cancer emerge, it becomes important to understand their unique characteristics and potential benefits.
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