| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2083319 | European Journal of Pharmaceutics and Biopharmaceutics | 2015 | 10 Pages |
Abstract
Chitosan and its derivatives have attracted great attention due to their properties beneficial for application to wound healing. The main focus of the present review is to summarize studies involving chitosan and its derivatives, especially N,N,N-trimethyl-chitosan (TMC), N,O-carboxymethyl-chitosan (CMC) and O-carboxymethyl-N,N,N-trimethyl-chitosan (CMTMC), used to accelerate wound healing. Moreover, formulation strategies for chitosan and its derivatives, as well as their in vitro, in vivo and clinical applications in wound healing are described.
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Authors
V. Patrulea, V. Ostafe, G. Borchard, O. Jordan,