Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2084767 | European Journal of Pharmaceutics and Biopharmaceutics | 2008 | 9 Pages |
Abstract
Polymeric drug-loaded nanoparticles have been extensively studied in the field of drug delivery. Biodistribution depends on the physicochemical properties of particles, especially size. The global message from the literature is that small particles have an enhanced ability to reach their target. The present review highlights the difficulties in validating the data from biodistribution studies without accurate particle size determination.
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Authors
Marie Gaumet, Angelica Vargas, Robert Gurny, Florence Delie,