| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2085239 | European Journal of Pharmaceutics and Biopharmaceutics | 2012 | 10 Pages |
Abstract
The biological performance of Oryzalin was improved by incorporation in liposomes with reduction of toxicity and haemolytic activity and increment of accumulation in the target organs of the disease (leishmaniasis).
Keywords
THP-1human monocytic cell linePhase transition temperaturesDPPGDMPGRBCsDinitroanilinesdMPCTFAMCLTFLFBSDPPCRed blood cellsTrifluoroacetic acidOryzalini.e.TrifluralindipalmitoylphosphatidylcholineDipalmitoylphosphatidylglycerolCutaneous leishmaniasisfoetal bovine serumpolydispersity indexLoading capacityl.c.LeishmaniasisVisceral leishmaniasismucocutaneous leishmaniasisLiposomesmean diameternanomedicinesZeta potential
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Authors
Rui M. Lopes, M. LuÃsa Corvo, Carla V. Eleutério, Manuela C. Carvalheiro, Effie Scoulica, M. Eugénia M. Cruz,