| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2089300 | Journal of Immunological Methods | 2006 | 6 Pages |
Abstract
β-Glucans are structural components of fungal cell walls which are involved in the immune recognition of fungal pathogens and possess beneficial immunomodulatory activities in isolated form. Here we have developed a soluble chimeric form of the major mammalian β-glucan receptor, Dectin-1, and demonstrate its application for the detection and characterisation of soluble and insoluble β-glucans, including fungal particles, using ELISA, flow cytometric and fluorescence-based microscopy assays.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biotechnology
Authors
Lisa M. Graham, S. Vicky Tsoni, Janet A. Willment, David L. Williams, Philip R. Taylor, Siamon Gordon, Kevin Dennehy, Gordon D. Brown,