Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2092578 | Microbiological Research | 2010 | 5 Pages |
Abstract
A family of 2-pyridineformamide-derived thiosemicarbazones and their gallium(III) complexes were tested against several isolates of pathogenic Cryptococcus strains. On complexation the antifungal activity significantly increases, suggesting coordination to gallium(III) to be an interesting strategy of antifungal dose reduction.
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Authors
Thaíssa de Oliveira Bastos, Betânia Maria Soares, Patrícia Silva Cisalpino, Isolda Castro Mendes, Raquel Gouvea dos Santos, Heloisa Beraldo,