| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2092647 | Microbiological Research | 2006 | 6 Pages |
Abstract
SummaryThe chemical investigation of the ethanolic extract of the root bark of Onosma hispidum following antibacterial activity directed isolation led to the isolation of 4-hydroxy-3-methoxy cinnamic acid (ferulic acid) and 4-hydroxy-3-methoxy benzoic acid (vanillic acid) which have been reported for the first time in this species. In addition to these compounds, the crude ethanolic extract and methanol fraction exhibited substantial bioactivity against species of corynebacteria, enterococci, staphylococci and streptococci. Ferulic acid was found more bioactive (being relatively more hydrophobic) compared to vanillic acid.
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Authors
Shahina Naz, Samia Ahmad, Sheikh Ajaz Rasool, Syed Asad Sayeed, Rahmanullah Siddiqi,