Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2100213 | Best Practice & Research Clinical Haematology | 2013 | 6 Pages |
Abstract
A number of new agents in acute myeloid leukemia (AML) have held much promise in recent years, but most have failed to change the therapeutic landscape. Indeed, with the exception of gemtuzumab ozogamicin (which was subsequently voluntarily withdrawn from the commercial market), no new agent has been approved for acute myeloid leukemia (AML) beyond the 7 + 3 regimen, which was has been in use for over 40 years. This review touches upon the potential reasons for these failures and explores the newer therapeutic approaches being pursued in AML.
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Authors
Jeffrey E. Lancet,