| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2103711 | Biology of Blood and Marrow Transplantation | 2011 | 6 Pages |
Abstract
Adoptively transferred T cells have shown activity in treating viral infections after hemopoietic transplantation and anti-tumor activity against some malignancies such as melanoma and lymphoma. Current research focuses on defining the optimum type of cell for transfer to improve persistence and genetically modifying infused T cells to augment function, overcome tumor evasion strategies and allow ablation should adverse effects occur.
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Authors
Chiara Bonini, Malcolm K. Brenner, Helen E. Heslop, Richard A. Morgan,