Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2107124 | Cancer Cell | 2012 | 4 Pages |
Abstract
Two recent papers published in Nature demonstrate the power of systematic high-throughput pharmacologic profiling of very large, diverse, molecularly-characterized human cancer cell line panels to reveal linkages between genetic profile and targeted-drug sensitivity. Known oncogene addictions are confirmed while surprising complexities and biomarker relationships with clinical potential are revealed.
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Authors
Paul Workman, Paul A. Clarke, Bissan Al-Lazikani,