| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2108928 | Cancer Epidemiology | 2012 | 4 Pages |
Abstract
microRNAs are genomically encoded small non-coding RNAs that regulate genetic information by controlling stability or translation of mRNAs. Down-regulated expression of microRNA-101 (miRNA-101) has been found in a variety of cancers, and associated with the invasion and progression of malignancies. Recent advances in the understanding of miRNA-101 biogenesis, target recognition and participation in regulatory pathways demonstrate a role for miRNA-101 in tumorigenesis. miRNA-101 gene therapy is of great potentiality to be a new modality for treatment of cancers.
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Authors
Ting Gui, Keng Shen,